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Antimicrobial acrylic coating modified with guanidinium oligomer

Writer's picture: Janet KohlmorgenJanet Kohlmorgen

Researchers describe the preparation and the properties of an antimicrobial acrylic coating modified with guanidinium oligomer.


An acrylic copolymer containing epoxy groups was synthesised by free radical polymerisation of glycidyl methacrylate, methyl methacrylate and butyl acrylate.


Afterwards, polyhexamethylene guanidine hydrochloride (PHMG) was chemically bonded with the resin through a reaction between the epoxy groups of the resin and the amino groups of PHMG to generate non-leaching and permanent antimicrobial acrylic coating.



Excellent antimicrobial property

When the content of PHMG reaches 1.0 wt%, the inhibition factors against E. coli and S. aureus were respectively 99.992% and 99.994%. The antimicrobial coating retains an excellent antimicrobial property even after being laundered with detergent solution. Moreover, the hydrophilicity of the antimicrobial coating was increased after the introduction of polar PHMG.

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